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Tamryn Burgess, R.H.N

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Can Taking Magnesium Make Anxiety Worse Before It Gets Better?

July 28, 2025Last Modified: July 29, 2025 by Tamryn Leave a Comment

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So you started taking magnesium for your anxiety and now you feel worse, and you’re spiraling because you’re convinced this means something is seriously wrong with you.

I get it. I’ve been there too.

When I first started taking magnesium, I was so desperate for relief from my anxiety that I would have tried anything. I ordered some magnesium glycinate after hearing how much it helped other people, and I was so hopeful that this would finally be the thing that made a difference.

But instead of feeling better, I felt… different. And not in a good way.

My stomach was upset, I felt tired in this weird way that I couldn’t explain, and of course, my health anxiety brain immediately jumped to the worst possible conclusions. I was convinced I was having an allergic reaction, or that my body was rejecting the supplement, or that something was seriously wrong with me.

I spent hours Googling “magnesium side effects” and “magnesium poisoning,” spiraling deeper into panic with every search result I read.

And when you have health anxiety, any change in your body can feel terrifying. You’re so hyperaware of every sensation that normal adjustment symptoms feel like warning signs of impending doom.

If you’re reading this because you’re going through something similar right now, I want you to know that you’re not alone, and you’re definitely not crazy.

In this post, I’m going to be sharing what I wish someone had told me when I first started taking magnesium – why it might make you feel worse before it makes you feel better, what’s normal versus what’s concerning, and how to get through this adjustment period without letting your anxiety completely take over.

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1. What’s Really Happening When You Start Taking Magnesium
2. Why Magnesium Might Make You Feel Worse Initially
3. What Normal Adjustment Symptoms Look Like
4. When You Should Actually Be Concerned
5. How I Learned to Navigate the Adjustment Period
6. Questions I Had (That You Probably Have Too)
7. Food Sources vs. Supplements
8. When Magnesium Actually Started Helping
9. Moving Forward: What I Want You to Remember

What’s Really Happening When You Start Taking Magnesium

Before we dive into why you might feel worse initially, let me explain what magnesium actually does in your body, because understanding this helped calm my racing mind so much.

Magnesium is involved in over 300 processes in your body. It helps regulate your nervous system by blocking glutamate (the neurotransmitter that makes you feel wired) and supporting GABA production (the neurotransmitter that helps you feel calm).

Here’s the thing though…

Most of us are magnesium deficient. We’ve been running our bodies on empty for so long that we’ve forgotten what it feels like to have normal levels.

When you suddenly start giving your magnesium-starved body what it needs, everything has to readjust which can start to create a vicious cycle. When you’re stressed, your body uses up magnesium faster. When you’re low on magnesium, you feel more stressed.

When you’ve been caught in this cycle for a long time, your body adapts to functioning in crisis mode. Your muscles stay tense, your nervous system stays activated, and everything feels heightened.

Introducing adequate magnesium breaks this cycle, but the transition can feel uncomfortable because you’re not used to your body actually being able to relax.

Think of it like this: if you’ve been clenching your jaw for hours and then suddenly relax it, that moment of release might feel strange or even uncomfortable, even though it’s exactly what your jaw needed.

Why Magnesium Might Make You Feel Worse Initially

Your Digestive System Rebels

This was the biggest issue for me.

Magnesium has a relaxing effect on your intestines, and when you first start taking it, your digestive system might not know what to do with this sudden relaxation.

Sorry if this is TMI, but I experienced:

  • Loose stools that had me convinced something was terribly wrong
  • Stomach cramping that sent me into a panic spiral
  • Bloating that made me feel uncomfortable and “off”
  • Nausea, especially when I took it without food

My health anxiety immediately latched onto these symptoms. I was sure I was having some kind of severe reaction, that my body couldn’t handle supplements, or that I had developed a serious digestive condition overnight.

But what was actually happening was completely normal. My body just needed time to adjust to this new level of magnesium.

Your Nervous System Starts to Actually Relax

When you’ve been anxious for a long time, your nervous system gets stuck in a state of hypervigilance. You’re constantly on edge, muscles tense, mind racing.

Magnesium helps your nervous system shift out of this state, but when you’re not used to feeling relaxed, “calm” can actually feel scary.

I remember feeling tired after taking magnesium and immediately panicking that something was wrong. But what was happening was that my chronically overstimulated nervous system was finally getting permission to rest, and I had forgotten what that felt like.

Other things I experienced:

  • Feeling emotionally different in a way I couldn’t describe
  • Mild headaches as my body adjusted
  • A weird sense of being “off” that I couldn’t pinpoint

Health Anxiety Makes Everything Feel Worse

Here’s something I learned that was huge for me…

When you have health anxiety, you become hyperaware of every tiny change in your body.

Most people might notice “oh, my stomach feels a bit different” and move on with their day. But we analyze every sensation, every twinge, every feeling that seems even slightly unusual.

The magnesium wasn’t necessarily making me feel worse, I was just paying attention to every single thing my body was doing and interpreting normal adjustment symptoms as signs of danger.

What Normal Adjustment Symptoms Look Like

Based on my experience and what I’ve learned since, here’s what typical magnesium adjustment symptoms include:

Digestive symptoms (usually first 1-2 weeks):

  • Loose stools or mild diarrhea
  • Some stomach cramping
  • Bloating
  • Nausea, especially on an empty stomach

Other symptoms (first few days to 2 weeks):

  • Feeling more tired than usual
  • Mild headaches
  • Feeling “different” or “off” without being able to explain why
  • Slight dizziness

Timeline that helped ease my anxiety:

  • First few days: Digestive changes most noticeable
  • First week: Peak adjustment period – you might question whether this is worth it
  • Week 2-3: Symptoms start settling
  • Month and beyond: Body adjusted, benefits become apparent

Research suggests that improvements in sleep and anxiety can occur within one to two weeks, but you have to get through the adjustment period first.

When You Should Actually Be Concerned

I don’t want to scare you, but there are some symptoms that aren’t normal and mean you should stop taking magnesium immediately:

Stop and seek medical help if you experience:

  • Severe diarrhea (more than a few loose stools)
  • Vomiting
  • Severe cramping or abdominal pain
  • Persistent dizziness
  • Irregular heartbeat or chest pain
  • Difficulty breathing
  • Severe fatigue that interferes with daily life

Taking too much magnesium can be dangerous, and people with kidney problems should avoid magnesium supplements altogether.

The key difference is severity and duration. Normal adjustment symptoms are mild and improve over time. Dangerous symptoms are severe, getting worse, or lasting longer than they should.

How I Learned to Navigate the Adjustment Period

Start Low and Go Slow

This is what I wish I had done from the beginning.

Experts recommend starting with around 100mg and gradually increasing.

I made the mistake of jumping straight to 400mg because I was impatient for results. Starting lower and increasing slowly would have made the adjustment so much easier.

Choose the Right Form

Not all magnesium supplements are created equal.

The forms you find at most drugstores – magnesium oxide and citrate – are poorly absorbed and more likely to cause digestive issues.

For anxiety, these forms work better:

  • Magnesium glycinate – my personal favorite, gentle on the stomach
  • Magnesium taurate – especially good if you also experience heart palpitations
  • Magnesium L-threonate – crosses the blood-brain barrier well

Take It With Food and At Night

Taking magnesium on an empty stomach made my nausea so much worse. Taking it with dinner eliminated most of the digestive discomfort.

Taking it before bed also helps because magnesium promotes relaxation and sleep. Plus, if it makes you tired, you’ll be sleeping anyway!

Questions I Had (That You Probably Have Too)

“Should I stop if I feel worse?” Not necessarily. If you’re experiencing mild digestive symptoms or fatigue, try lowering your dose and giving it another week or two. If symptoms are severe or getting worse, then yes, stop and talk to a healthcare provider.

“How do I know if it’s the magnesium or my anxiety making me feel worse?” This is really hard to distinguish when you have health anxiety. Generally, magnesium adjustment symptoms are more physical (digestive issues, fatigue), while anxiety symptoms tend to be more mental/emotional with physical manifestations.

“What if I can’t tolerate any magnesium?” Some people genuinely can’t tolerate certain forms. Try a different type or focus on getting magnesium from food sources instead.

“Is feeling tired normal?” Yes, especially if you’ve been running on anxiety and adrenaline. When your nervous system finally gets permission to relax, fatigue is common.

Food Sources vs. Supplements

Before jumping into supplements, getting magnesium from food is always gentler on your system.

Good food sources include:

  • Dark leafy greens
  • Almonds and pumpkin seeds
  • Dark chocolate (85% or higher)
  • Avocados
  • Black beans

The advantage of food sources is they’re less likely to cause digestive upset. The downside is it’s harder to get therapeutic amounts if you’re significantly deficient.

When Magnesium Actually Started Helping

I wanna be totally honest here…

The benefits weren’t immediate or dramatic.

The first thing I noticed was slightly better sleep quality. Not falling asleep faster necessarily, but staying asleep better and feeling more rested.

Over time, my heart palpitations decreased significantly though!

This was huge because palpitations were one of my biggest anxiety triggers.

Muscle tension improved gradually too. I didn’t realize how much tension I was carrying until it started releasing.

Research shows that magnesium affects the hypothalamus, which regulates your stress response system. But these changes take time to become noticeable.

Moving Forward: What I Want You to Remember

Starting something new when you have health anxiety is terrifying. Literally every body sensation feels like a death sentence, and the idea of feeling worse before feeling better sounds impossible to endure.

But here’s what I want you to know…

Your body wants to heal. When you give it what it needs, it will work toward balance, even if that process feels uncomfortable initially.

The difference between normal adjustment and something dangerous is usually clear. Normal symptoms are mild and improve over time, while concerning symptoms are severe or worsening.

Most importantly, trust yourself.

If something feels truly wrong (not just different), get medical advice. But if you’re experiencing mild symptoms in those first couple weeks, try to be patient with the process.

Magnesium has made such a difference in my anxiety management, but I almost gave up during that first difficult week. I’m so grateful I didn’t.

If you’re looking for comprehensive guidance on supplements for anxiety, I created a free guide called “5 Daily Supplements To Help You Better Manage Stress and Anxiety” that includes everything I’ve learned about magnesium and four other supplements that have been game-changers for me.

For even more detailed information about managing every aspect of anxiety naturally, my Anxiety A to Z Encyclopedia covers over 600 pages of symptoms, coping strategies, and supplement recommendations based on my years of research and personal experience.

Remember, having health anxiety doesn’t make you weak or crazy. It makes you human. Be gentle with yourself as you navigate this journey, and know that it’s possible to feel better, even if the path there feels scary sometimes.

You’re going to be okay. ❤️

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About Tamryn

Hi! I'm Tamryn, Registered Holistic Nutritionist and blogger here at Honestly Holistic. I went from "dealing" with anxiety to healing, naturally. I now help others do the same.⁣

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As a Registered Holistic Nutritionist™, it is my goal to help you make sense of the nutrition information overload we all experience daily. I’ll be your mentor, supporting you through your own individualized journey. We’ll work together, freeing you from symptoms by addressing the underlying root cause of what is troubling you. Read More…

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